Purpose: This study is to learn whether phage, viruses designed to attack bacteria, are a safe and effective form of treatment for foot ulcers associated with foot bone infections in patients with diabetes.
Diabetes can lead to foot ulcers which can lead to serious complications.
People with diabetes often develop peripheral neuropathy, or damaged nerves, in their feet related to low blood flow. These damaged nerves and low blood flow can lead to numbness and tingling as well as sores and blisters.
When the sores are open, they're called ulcers and can become infected. The infected ulcer can lead to an infection in the foot bone and become very serious. If left untreated, a neglected ulcer can lead to amputation.
What is a phage?
Phages are viruses specialized to only kill harmful bacteria and not healthy human cells. They are the most abundant biological entities found in nature. Phages are found in all parts of the body and, as a result, we are continuously exposed to many kinds of phage.
This study is to learn whether phage can effectively treat diabetic foot ulcers.
What to expect as a part of this trial:
First see if you meet three basic qualifications and you'll be directed to a clinic in your area. They will set up a time with you to finish the screening process. If you are a match and want to participate, they'll walk you through the steps for enrollment and informed consent process.
Patients choosing to participate in this study will be asked to undergo screening tests (such as blood tests, wound cultures, and bone biopsy) or procedures to find out if they are eligible.
Interested in joining this trial?
Just 3 simple questions to get started:
1 Are you between 18 and 85 years old?
2 Do you have diabetes?
3 Do you have a foot ulcer?
Note: Other conditions not specified above may result in exclusion from the study.
If you answer yes to all three questions,
you may qualify to participate in a research study that may help.